| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8644563 | Gene | 2018 | 27 Pages |
Abstract
Our results indicated that three functional polymorphisms (rs2297136, rs4143815 and rs17718883) of the PD-L1 gene were associated with HCC risk and prognosis, suggesting that genetic variants of PD-L1 polymorphisms might be a possible prognostic marker for the prediction of HCC risk and development. Validation by a larger prospective study from a more diverse ethnic population is needed to confirm these findings.
Keywords
FDAPD-1TACESNPsPD-L1HCCoverall survivalELISAEnzyme-linked immunosorbent assaySusceptibilityPCR-RFLPFood and Drug AdministrationNSCLCNon-small cell lung cancerodds ratioSingle nucleotide polymorphisms (SNPs)Single nucleotide polymorphismspolymerase chain reaction-restriction fragment length polymorphismprognosisHepatocellular carcinoma
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Genetics
Authors
Qigui Xie, Zhanlei Chen, Liang Xia, Qiufeng Zhao, Haitao Yu, Zhuying Yang,