Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8645329 | Gene | 2018 | 4 Pages |
Abstract
Aggressive behavior represents an important public concern and a clinical challenge to behaviorists and psychiatrists. Aggression in humans is known to have an important genetic basis, so to investigate the association of Y chromosome short tandem repeat (Y-STR) loci with initiative-aggressive behavior, we compared allelic and haplotypic distributions of 22 Y-STRs in a group of Chinese males convicted of premeditated extremely violent crimes (nâ¯=â¯271) with a normal control group (nâ¯=â¯492). Allelic distributions of DYS533 and DYS437 loci differed significantly between the two groups (Pâ¯<â¯0.05). The case group had higher frequencies of DYS533 allele 14, DYS437 allele 14, and haplotypes 11-14 of DYS533-DYS437 compared with the control group. Additionally, the DYS437 allele 15 frequency was significantly lower in cases than controls. No frequency differences were observed in the other 20 Y-STR loci between these two groups. Our results indicate a genetic role for Y-STR loci in the development of initiative aggression in non-psychiatric subjects.
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Genetics
Authors
Chun Yang, Huajie Ba, Wei Zhang, Shuyou Zhang, Hanqing Zhao, Haiying Yu, Zhiqin Gao, Binbin Wang,