Hepatic transcriptional profiling response to fava bean-induced oxidative stress in glucose-6-phosphate dehydrogenase-deficient mice

Article ID	Journal	Published Year	Pages	File Type
8645398	Gene	2018	46 Pages	PDF

Abstract

G6PD mutant allele was verified by PCR-RFLP and the G6PD activity assay, while number of genes expression was altered in C3H and G6PDx mice after FB ingestion.114

Keywords

DTNB d-glucose-6-phosphate INSIG1 PHZ MDA PCK1 metallothionein 1 MT1 CYP450 G6P PNT GSSG qRT-PCR GSH CAT NADPH G6PD TBA 2-Thiobarbituric acid 5,5′-dithiobis-(2-nitrobenzoic acid)ROS real-time quantitative RT-PCR Oxidative stress sequencing DAVID PCR-RFLP SOD Superoxide dismutase Cytochrome P450 Phenylhydrazine Fava bean malondialdehyde wild type nicotinamide adenine dinucleotide phosphate Gene ontology database for annotation, visualization and integrated discovery Phenacetin Catalase Glutathione oxidized glutathione glucose 6-phosphate dehydrogenase glucose-6-phosphate dehydrogenase Reactive oxygen species

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Genetics

Hepatic transcriptional profiling response to fava bean-induced oxidative stress in glucose-6-phosphate dehydrogenase-deficient mice

Authors

Guankui Du, Man Xiao, Xiuyu Wei, Chen Zhou, Shuoshuo Li, Wangwei Cai,