| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8645804 | Gene | 2018 | 41 Pages |
Abstract
YPEL1 and YPEL5 may be related to the action of erlotinib, and down-regulation of ITGA2 may be associated with the development of acquired resistance to erlotinib in EGFR-mutant NSCLCs. Furthermore, several small-molecule drugs that may have synergistic and antagonistic roles with erlotinib were identified.
Keywords
zinc finger E-box-binding homeobox 1RMAAXL receptor tyrosine kinaseover-representation analysisTKIsZEB1EGFRCMAPDEGsCK1αSmall-molecule drugsGEODTPSPPIGABARAPL1DMSOErlotinibAxlMolecular functionProtein-protein interactionfold changeEMTcellular componentKEGG یا Kyoto Encyclopedia of Genes and Genomes DAVIDDimethyl sulfoxideNSCLCNon-small cell lung cancerORAbiological processTyrosine kinase inhibitorsconnectivity mapGene ontologyDatabase for Annotation, Visualization, and Integrated DiscoveryGene Expression OmnibusDifferentially expressed genesEpithelial-mesenchymal transitionEpidermal growth factor receptor
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Genetics
Authors
Xiaoli Wu,