| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8646072 | Gene | 2018 | 6 Pages |
Abstract
MMP9, OPN, TP53 and CDKN2A were the identified markers that were expressed in a similar pattern in early embryonic development and cancer development & invasion suggesting that these genes are activated during embryogenesis and might be re-expressed in cancer metastasis. Moreover, these genes govern a pathway that might be activated during cancer metastasis. Thus, targeting these molecules may provide better treatment for metastatic liver cancers.
Keywords
TP53C-X-C motif chemokine ligand 12HIF-1ATGFBR2Matrix metalloproteinases 9CTNNB1SPP1MUC16cyclin dependent kinase inhibitor 2ACDKN2ACLDN4CDH1CK7OPNCXCL12CXCR4qRT-PCRMMP-9VEGFAE-cadherinOsteopontinepithelial mesenchymal transitionbeta cateninEMTPrimary liver cancercytokeratin-7Vascular endothelial growth factor ALiver metastasisGene profilingC-X-C chemokine receptor type 4quantitative real time polymerase chain reactiontumor protein 53Fetal liverClaudin-4
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Authors
Kanisha Shah, Shanaya Patel, Sheefa Mirza, Rakesh M. Rawal,