Computational elucidation of novel antagonists and binding insights by structural and functional analyses of serine hydroxymethyltransferase and interaction with inhibitors

Article ID	Journal	Published Year	Pages	File Type
8646248	Gene Reports	2018	40 Pages	PDF

Keywords

THF GROningen MAchine for Chemical Simulations GROMACS PLP SHMT PDB RMSD NCBI discrete optimized protein energy tetrahydrofolate Protein structure analysis Docking Root Mean Square Deviations serine hydroxymethyltransferase thymidylate synthase Molecular dynamics simulation Leishmania donovani Homology modeling National Center for Biotechnology Information Protein Data Bank PROSA Pyridoxal phosphate DOPE

Related Topics

Life Sciences Biochemistry, Genetics and Molecular Biology Genetics

Computational elucidation of novel antagonists and binding insights by structural and functional analyses of serine hydroxymethyltransferase and interaction with inhibitors

Authors

Manas R. Dikhit, Md Yousuf Ansari, Sahil sinha, Vahab Ali, Roshan Kamal Topno, Jyoti Prava Majhee, Ganesh C. Sahoo, Pradeep Das,