| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8647309 | Multiple Sclerosis and Related Disorders | 2018 | 25 Pages |
Abstract
Although the DMF/MMF mechanism of action remains unclear, evidence suggests that the activation of HCA2/GPR109A pathway downregulates the immune response and may activate anti-inflammatory response in the intestinal mucosa, possibly leading to reduction in CNS tissue damage in MS patients.
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Authors
Felipe von Glehn, Rafael P.C. Dias-Carneiro, Adriel S. Moraes, Alessandro S. Farias, Veronica A.P.G. Silva, Francisco T.M. Oliveira, Carlos Eduardo B.G. Silva, Fabricio de Carvalho, Elaine Rahal, Clare Baecher-Allan, Leonilda M.B. Santos,