Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8648535 | Molecular Immunology | 2018 | 11 Pages |
Abstract
This report, for the first time, clarifies the relative bactericidal contributions of NETs and complement. We propose that - while NETs can ensnare bacteria such as P. aeruginosa - complement is necessary for efficient bacterial killing.
Keywords
Terminal pathwayphorbol 12-myristate 13-acetateNHSCFUPMAMOINETsneutrophil extracellular trapsstandard error of meanHISnormal human serumcytochalasin DComplementSEMalternative pathwaylectin pathwayclassical pathwayMACNeutrophilscolony forming unitsPropidium iodidemultiplicity of infectionoptical densityErythrocyte
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Authors
Louiza Azzouz, Ahmed Cherry, Magdalena Riedl, Meraj Khan, Fred G. Pluthero, Walter H.A. Kahr, Nades Palaniyar, Christoph Licht,