The genes involved in asthma with the treatment of human embryonic stem cell-derived mesenchymal stem cells

Article ID	Journal	Published Year	Pages	File Type
8648568	Molecular Immunology	2018	9 Pages	PDF

Abstract

The therapeutic effects of hESC-MSCs were identified in the murine model of airway allergic inflammation with key mRNAs involved. This study will provide a better understanding regarding the mechanisms underlying hESC-MSCs therapeutic application in airway allergic inflammation.

Keywords

PDCD1 IPSCs OVA hESCs CCL Treg bFGF MSCs WGS CGH APC FBS FACS PBS Type 2 helper T cell Th2 EGF NEAA BM-MSC mRNAs H&E T regulatory PCR array Asthma allophycocyanin non-essential amino acid periodic acid–Schiff Ovalbumin immunoglobulin interleukin BALF phosphate buffer ANOVA one-way analysis of variance comparative genomic hybridization ELISA Enzyme-linked immunosorbent assay Whole genome sequencing cluster of differentiation fetal bovine serum human embryonic stem cells Mesenchymal stem cells Bone marrow-derived mesenchymal stem cell Induced pluripotent stem cells epidermal growth factor basic fibroblast growth factor phycoerythrin fluorescence activated cell sorting chemokine (C-C motif) ligand Bronchoalveolar lavage fluid programmed cell death 1 PAS haematoxylin and eosin polymerase chain reaction PCR Single nucleotide polymorphism SNP