| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8648624 | Molecular Immunology | 2018 | 10 Pages |
Abstract
Collectively, our study suggests that differential effects of LPS on TNF-α mRNA turnover and on signal transduction pathways influence the amount of TNF-α finally produced by GM-MΦ and M-MΦ.
Keywords
TLR4TRIF-related adapter moleculeTIRAPTTPIRF3ActDMYD88LPSIFNARMϕTRIFmyeloid differentiation primary response 88actinomycin DTIR-domain-containing adapter-inducing interferon-βTRAMTristetraprolinmRNA stabilitycolony stimulating factorInterferon regulatory factor 3TNF-αMacrophage polarizationMacrophageCSFSignal transductionToll-like receptor 4
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Molecular Biology
Authors
Erik Schilling, Ronald Weiss, Anja Grahnert, Michael Bitar, Ulrich Sack, Sunna Hauschildt,