Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8649682 | Clínica e Investigación en Arteriosclerosis | 2018 | 11 Pages |
Abstract
As a prevalent cardiovascular disease, heart failure is one of the leading causes of morbidity and premature mortality. Therefore, there is a special interest in the study of efficient markers associated with risk and / or prediction of cardiovascular events. Multiple candidates are proposed, especially those involved in oxidative and inflammatory processes typical of cardiovascular disease, such as superoxide anion, nitric oxide, and peroxynitrite. There is a lack of knowledge on the potential usefulness of these systems as biomarkers. This review aims to contribute to a better understanding of these systems, as well as an improved patient profile. Furthermore, a deep knowledge of these complex systems would also allow proposing new lines of research for the development of new therapeutic tools as a promising start for new approaches to this disease.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Physiology
Authors
Roberto Bonafede, Walter Manucha,