Article ID Journal Published Year Pages File Type
8650452 Physiology & Behavior 2018 31 Pages PDF
Abstract
Our data demonstrate that the GLP-1/GLP-2 co-agonists have effects on gut morphometry, showing a marked increase in intestinal volume and mucosal surface area. Furthermore, effects on glucose tolerance and long-term glycemic control are evident. Effects on body weight and gastric emptying are also observed depending on the pharmacokinetic properties of the molecule. We suggest that this novel co-agonistic approach could exemplify a novel concept for treatment of T2DM or SBS.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Physiology
Authors
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