| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8650820 | Respiratory Physiology & Neurobiology | 2018 | 8 Pages |
Abstract
We tested the functional effects of hypoglossal (CNXII) stimulation in the anesthetized rabbit before and after injections of saline into the tongue base to obstruct the airway. Data (nâ¯=â¯6) show little or no effect of CN XII trunk stimulation; however, medial branch stimulation (20-100â¯Hz; 50-500â¯Î¼s pulse width, and incremental increases from 10â¯Î¼A) reduced upper airway resistance. Medial branch stimulation was less effective in reducing resistance than anterior advancement of the hyoid. Endoscopic viewing (n-3) of the retropalate showed this region as the narrowest and dynamically changed by anterior hyoid displacement, with less evident effects than CNXII stimulation. We conclude that under these conditions CNXII medial branch stimulation reduces airway resistance, especially after induced obstruction.
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Authors
Girriso F. Benderro, Jenniffer Gamble, Matthew A. Schiefer, Jonathan Z. Baskin, Yeritza Hernandez, Kingman P. Strohl,