Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8653100 | The Annals of Thoracic Surgery | 2017 | 7 Pages |
Abstract
Ischemic patients have aberrant mitochondrial function, highlighted by a lowered RCR. All ratios involving complex I were affected, suggesting that the insufficient ATP formation is predominantly due to complex I dysfunction. Complex II and IV respiration may be impaired as well, but to a lesser extent.
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Authors
David A. BS, Ryan BS, Katherine M. BS, Connor BS, Destiny S. BA, Scott MD, Toshinobu MD, PhD, Kitsie BA, Ryszard T. PhD, Dirk J. MD, PhD, Zain MD, PhD,