Article ID Journal Published Year Pages File Type
8656926 Atherosclerosis 2018 21 Pages PDF
Abstract
Our data demonstrate that reduced FOXP3 expression and Treg function in AAA patients are regulated by SIRT1-induced FOXP3 deacetylation. EX-527 could up-regulate FOXP3 acetylation and increase number and suppressive function of Treg in AAA patients.
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Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
Preview
Abnormal acetylation of FOXP3 regulated by SIRT-1 induces Treg functional deficiency in patients with abdominal aortic aneurysms
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