| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8656987 | Atherosclerosis | 2018 | 45 Pages |
Abstract
In this review, we describe the role of monocytes/macrophages and neutrophils in atherosclerosis, outline mechanisms of activation of the NLRP3 inflammasome in the setting of atherosclerosis-associated inflammation and discuss potential therapies that specifically target the NLRP3 inflammasome and/or its downstream mediators in atherosclerosis, with a particular focus on the emerging role of colchicine.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Gonzalo J. MartÃnez, David S. Celermajer, Sanjay Patel,