Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8657081 | Atherosclerosis | 2017 | 12 Pages |
Abstract
Statin treatment has no effect on local atherosclerotic lesion Lp-PLA2 activity, therefore, the addition of anti-inflammatory treatments to further decrease macrophage Lp-PLA2 expression in atherosclerotic lesions may reduce lesional inflammation and cell death, and prevent necrotic core expansion and lesion progression.
Keywords
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Fumiyuki Otsuka, XiaoQing Zhao, Hugh H. Trout, Ye Qiao, Bruce A. Wasserman, Masataka Nakano, Colin H. Macphee, Martin Brandt, Sue Krug-Gourley, Liang Guo, Elena R. Ladich, Qi Cheng, Harry R. Davis, Aloke V. Finn, Renu Virmani, Frank D. Kolodgie,