| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8657930 | Chest | 2018 | 13 Pages |
Abstract
These findings suggest that activation of HDAC2 and/or inhibition of IL-17A production could prevent the development of airway remodeling by suppressing airway inflammation and modulating fibroblast activation in COPD.
Keywords
TGF-β1CSET helper 17HDACRORγtCXCLHDAC2Th17HBEECMHRCThigh-resolution CTSmall interfering RNAsiRNAAirway inflammationhuman bronchial epithelialAirway remodelingCOPDtransforming growth factor beta 1Cigarette smokecigarette smoke extractchemokine (C-X-C motif) ligand Extracellular matrixwild-typeIl-17ahistone deacetylase
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Authors
Tianwen MD, PhD, Baoping MD, PhD, Chao MD, PhD, Yue MD, PhD, Jiesen MD, PhD, Yong MD, PhD, Yanping MD, PhD, Zhouyang MD, PhD, Xuchen MD, PhD, Min BA, Feng MD, PhD, Yuan MD, Min MD, Dong MD, Bin MD, Chen PhD, Wen MD, PhD, Songmin PhD, Huahao MD, PhD,