Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8658090 | Chest | 2018 | 62 Pages |
Abstract
Subgroups of smokers defined by upper-lobe or lower-lobe emphysema predominance exhibit different functional and radiological disease progression rates, and the upper-lobe predominant subtype shows evidence of association with known COPD genetic risk variants. These subgroups may be useful in the development of personalized treatments for COPD.
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Authors
Adel MD, Yale PhD, Michael H. MD, MPH, George R. MD, Raul PhD, Russell P. MD, James D. MD, Dawn L. MD, MPH, Jennifer G. PhD, Edwin K. MD, PhD, Peter J. MD,