| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8658091 | Chest | 2018 | 25 Pages |
Abstract
TREM-2 expression is increased in lung macrophages in COPD, particularly in comparison with TREM-1. Therefore, TREM-2 levels and the ratio of TREM-2/TREM-1 signifies M2 activation in COPD lung tissues and may help to guide therapeutics directed against the type 2 immune response in patients with this disease.
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Authors
Derek E. MD, PhD, Kangyun PhD, Geoffrey MD, Xiaohua MD, Eugene PhD, Xiaofeng MD, John T. MD, Kenneth PhD, Roger MD, MPH, Richard A. PhD, Michael J. MD,