| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8660419 | Heart Rhythm | 2017 | 8 Pages |
Abstract
Differences exist between rabbit atrial and ventricular myocytes in the biophysical properties of INa. The more negative voltage dependence of INa activation and inactivation, together with trapping of the drug in the inactivated channel, underlies an atrial-selective action of ranolazine.
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Authors
Rachel E. PhD, Hongwei PhD, Stéphanie C. PhD, Hanne C. PhD, Simon M. PhD, Jules C. PhD, FRSB, FBPhS, Andrew F. DPhil,