| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8661769 | International Journal of Cardiology | 2018 | 7 Pages |
Abstract
Plasma TMAO was associated with and improved reclassification of incident AF in two independent Norwegian cohorts with long-term follow-up. The relationship was independent of traditional AF risk factors, as well as of dietary choline intake. Our findings motivate further studies to explore endogenous metabolic factors influencing the relationship between TMAO and cardiovascular disease.
Keywords
ADMAEGFRFMO3LVEDPTMAOICCNRILVEFstandard deviationHuskNet reclassification improvementcardiovascular diseaseBiomarkerTrimethylamine-n-oxideasymmetric dimethylarginineCVDintraclass correlation coefficientCardiovascular disease risk factorsleft ventricular end-diastolic pressureAtrial fibrillationestimated glomerular filtration ratehazard ratioleft ventricular ejection fractionCholine
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Authors
Gard F.T. Svingen, Hui Zuo, Per M. Ueland, Reinhard Seifert, Kjetil H. Løland, Eva R. Pedersen, Peter M. Schuster, Therese Karlsson, Grethe S. Tell, Hall Schartum-Hansen, Hilde Olset, Mads Svenningsson, Elin Strand, Dennis W. Nilsen, Jan E. Nordrehaug,