Article ID Journal Published Year Pages File Type
8661814 International Journal of Cardiology 2018 6 Pages PDF
Abstract
This study-level meta-analysis of CRTs demonstrates that, compared to medical therapy, PFO closure prevents recurrent ischemic cerebral events, but increases the risk of AF/flutter in patients with cryptogenic stroke; as a result, the net clinical benefit with the two strategies was similar. Our results support an individualized therapeutic approach, tailored on the evaluation of the patient's risks (anatomical PFO risk, clinical risk of recurrent stroke, bleeding risk, and risk of AF).
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