Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8661814 | International Journal of Cardiology | 2018 | 6 Pages |
Abstract
This study-level meta-analysis of CRTs demonstrates that, compared to medical therapy, PFO closure prevents recurrent ischemic cerebral events, but increases the risk of AF/flutter in patients with cryptogenic stroke; as a result, the net clinical benefit with the two strategies was similar. Our results support an individualized therapeutic approach, tailored on the evaluation of the patient's risks (anatomical PFO risk, clinical risk of recurrent stroke, bleeding risk, and risk of AF).
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Authors
Vincenzo Pasceri, Francesco Pelliccia, Edoardo Bressi, Ludmilla Mantione, Carlo Gaudio, Giulio Speciale, Roxana Mehran, George D. Dangas, Giuseppe Patti,