| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8662198 | International Journal of Cardiology | 2018 | 10 Pages |
Abstract
Activation of AMPK protects against necroptosis via promoting Keap1-mediated PGAM5 degradation. Metformin may act as a valuable agent for the protection of myocardial ischemia and reperfusion injury by activating AMPK and reducing necroptosis.
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Authors
Yi-Shu Wang, Peng Yu, Yong Wang, Jing Zhang, Wei Hang, Zhi-Xian Yin, Gang Liu, Jianfeng Chen, Kaitlin D. Werle, Cheng-Shi Quan, Hang Gao, Qinghua Zeng, Rutao Cui, Jiyong Liang, Qiang Ding, Yu-Lin Li, Zhi-Xiang Xu,