Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8662442 | International Journal of Cardiology | 2018 | 8 Pages |
Abstract
Our data suggest that Gq-coupled M1-receptors also regulate human atrial IK,ACh and that their relative contribution to IK,ACh activation is increased in cAF patients. We provide novel insights about the role of non-M2-receptors in human atrial cardiomyocytes, which may have important implications for understanding AF pathophysiology.
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Authors
Jordi Heijman, Dorit Kirchner, Franziska Kunze, Eva Maria Chrétien, Martina B. Michel-Reher, Niels Voigt, Michael Knaut, Martin C. Michel, Ursula Ravens, Dobromir Dobrev,