| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8662469 | International Journal of Cardiology | 2018 | 5 Pages |
Abstract
High circulating OPN levels were strongly correlated with vulnerability parameters within plaques and predict MACEs in patients with severe carotid artery stenosis. Although confirmation is needed from larger trials, OPN could be a promising clinical tool to assess atherosclerotic outcomes.
Keywords
MMPMACEIL-6ECSThsCRPHDLACSTACSOPNCeAAtherosclerosisOsteopontininflammationCarotid endarterectomyinterleukin-6major adverse cardiovascular eventsEuropean Carotid Surgery TrialAsymptomatic Carotid Surgery Trialacute coronary syndromesIschemic strokehigh-density lipoprotein cholesterolLDLmatrix metalloproteinaseMacrophagehigh sensitivity C-reactive proteinLow-density lipoprotein cholesterol
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Authors
Federico Carbone, Fabio Rigamonti, Fabienne Burger, Aline Roth, Maria Bertolotto, Giovanni Spinella, Bianca Pane, Domenico Palombo, Aldo Pende, Aldo Bonaventura, Luca Liberale, Alessandra Vecchié, Franco Dallegri, François Mach, Fabrizio Montecucco,