Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8662850 | International Journal of Cardiology | 2017 | 13 Pages |
Abstract
This review provides a comprehensive update on the current state of LAAC in the field of prevention of death, stroke and bleedings in patients suffering from nonvalvular AF. We describe the pathophysiology of the LAA with regard to stroke, elucidate the evidence and limitations of anticoagulation as the classical treatment paradigm, and review devices and techniques for LAAC. Most importantly, the current clinical evidence on efficacy and safety is outlined and finally, contemporary recommendations for patient selection are provided.
Keywords
LAACPFOTEEVKAPCINOACINRTAVRTIADAPTCMSLAAOACACPRRRFDAVARCCardiac computed tomography angiographyElectrophysiologyintracardiac echocardiographyTransesophageal echocardiographyBARCleft atrial appendage closurePatent foramen ovaleTranscatheter aortic valve replacementcomputed tomographytransient ischemic attackESCBleedingBleeding Academic Research Consortiumdual antiplatelet therapycCTAStrokeleft atrial appendageFrenchAtrial fibrillationInternational Normalized Ratioatrial septal defectASDAnticoagulationAmplatzer Cardiac Plugrelative risk reductionValve Academic Research ConsortiumIce
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Authors
Steffen Gloekler, Jacqueline Saw, Konstantinos C. Koskinas, Caroline Kleinecke, Werner Jung, Fabian Nietlispach, Bernhard Meier,