Article ID Journal Published Year Pages File Type
8668333 Journal of Clinical Lipidology 2018 12 Pages PDF
Abstract
These unexpected findings indicate that measuring the circulating levels of the various domains and PTMs of PCSK9 provides more in depth information than total PCSK9 and that the prodomain and the phosphorylated state of S688 may represent novel biomarkers to explore in cardiometabolic diseases and response to treatment. In addition, our data generated new hypotheses on the function of PCSK9 PTMs in health and disease.
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Health Sciences Medicine and Dentistry Cardiology and Cardiovascular Medicine
Authors
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