Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8668543 | Journal of Clinical Lipidology | 2017 | 13 Pages |
Abstract
Mutation-negative FH subjects accumulate an excess of rare and common gene variations in ABCG5/G8 genes. This variation is associated with increased intestinal absorption of cholesterol, as determined by surrogate makers, suggesting that these loci contribute to hypercholesterolemia by enhancing intestinal cholesterol absorption.
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Authors
Itziar MSc, LucÃa PhD, Ana M. MLT, RocÃo PhD, SofÃa MSc, Victoria MSc, Antonio PhD, Emilio PhD, MD, Montserrat PhD, José Carlos PhD, Miguel PhD, Ana PhD, Fernando PhD, MD,