| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8669254 | The Journal of Heart and Lung Transplantation | 2018 | 25 Pages |
Abstract
Treatment of 24-hour-preserved pig donor lungs with A1AT during EVLP resulted in improved physiologic function, reduced pulmonary edema and inflammation and decreased cell death. Our findings suggest that treatment of donor lungs during EVLP with A1AT is a promising strategy to attenuate early lung injury and improve donor lung function before lung transplantation.
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Authors
Huiqing MD, PhD, Manyin MD, Feng MD, PhD, Jussi MD, PhD, Lei MD, Hei Yu BSc, Daisuke MD, PhD, Zhe MD, PhD, Andrea MD, David MD, PhD, Marcelo MD, MSc, Shaf MD, MSc, Mingyao MD, MSc,