Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8671199 | The Journal of Thoracic and Cardiovascular Surgery | 2017 | 10 Pages |
Abstract
The RV adaptive response to chronic pressure overload differs between 2 different piglet models of PH. Mismatch between angiogenesis and workload (CD to stroke work ratio) was associated with greater degree of myocardial fibrosis and RV dysfunction and could be a promising index of RV maladaptation. Further studies are needed to understand the underlying mechanisms.
Keywords
CTEPHAdaptive remodelingRVFACmPAPEESAngiogenesisVentricular elastanceright ventricleCapillary densityright ventricular fractional area changeEisenmenger syndromecardiac indexPulmonary arteryVascular Endothelial Growth Factor (VEGF)Vascular Endothelium Growth Factormean pulmonary arterial pressureChronic thromboembolic pulmonary hypertensionFibrosisPulmonary hypertensionStroke work
Related Topics
Health Sciences
Medicine and Dentistry
Cardiology and Cardiovascular Medicine
Authors
Pierre-Emmanuel MD, MSc, François MD, Jennifer MSc, Nathaniel MD, Peter MD, PhD, Fanny MSc, Julien MD, MSc, Benoit MSc, Lilia MSc, Elie MD, PhD, Olaf MD, PhD,