On the influence of wall calcification and intraluminal thrombus on prediction of abdominal aortic aneurysm rupture

The mechanical-structural calcification information presented in this study marks a crucial starting point for a risk-benefit analysis to better predict abdominal aortic aneurysm rupture risk. Calcification plays an integral role in the structural degradation of abdominal aortic aneurysm walls, which is mechanically represented by diminished stiffness properties. This degradative influence coupled with significant straining influences of calcification predisposes surrounding noncalcified tissue to significantly increased stresses, which may help disclose the wall's localized site of highest rupture risk. Thus, this information may help assess whether a survival benefit can be achieved from clinical intervention.