| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8671769 | Journal of Vascular Surgery | 2018 | 11 Pages |
Abstract
We aimed to assess the diagnostic accuracy of procalcitonin (PCT) compared with other traditional markers and its association with inflammatory cytokines. The findings showed a significant difference in the levels of PCT up to sevenfold in infected diabetic foot ulcer (DFU) compared with noninfected DFU, which was better than for other traditional markers, such as C-reactive protein levels, white blood cell count, and erythrocyte sedimentation rate. Moreover, PCT was found to have positively correlated with helper T-cell subtypes 1 and 17 inflammatory cytokines. Based on our findings, we could clinically use PCT as a marker to distinguish the mild line between infected and noninfected DFUs.
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Authors
Dhamodharan PhD, Sireesh MSc, Arvind D'Orth, Narayana FRCS, Vairamani PhD, Rajesh MS, Ramkumar PhD,