A glucose biosensor based on TiO2–Graphene composite

A novel glucose biosensor was developed based on the adsorption of glucose oxidase at a TiO2–Graphene (GR) nanocomposite electrode. A TiO2–GR composite was synthesized from a colloidal mixture of TiO2 nanparticles and graphene oxide (GO) nanosheets by an aerosol assisted self-assembly (AASA). The particle morphology of all TiO2–GR composites was spherical in shape. It was observed that micron-sized TiO2 particles were encapsulated by GR nanosheets and that the degree of encapsulation was proportional to the ratio of GO/TiO2. The amperometric response of the glucose biosensor fabricated by the TiO2–GR composite was linear against a concentration of glucose ranging from 0 to 8 mM at −0.6 V. The highest sensitivity was noted at about 6.2 μA/mM cm2. The as prepared glucose biosensor based on the TiO2–GR composite showed higher catalytic performance for glucose redox than a pure TiO2 and GR biosensor.

► A TiO2–graphene (GR) composite was prepared via the aerosol assisted self-assembly. ► The composite showed better catalytic performance for glucose redox than a GR or a TiO2. ► This demonstrates the synergistic effect of using TiO2 with GR as the electrode materials. ► The TiO2–GR composite shows promise as an enhanced glucose biosensor.