| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8674180 | Molecular Metabolism | 2018 | 10 Pages |
Abstract
Although less well studied than effects of gonadal hormones, sex chromosomes exert independent and interactive effects on adiposity, lipid metabolism, and inflammation. In particular, the presence of two X chromosomes has been associated with increased adiposity and dyslipidemia in mouse models and in XXY men. The enhanced expression of genes that escape X chromosome inactivation may contribute, but more work is required.
Related Topics
Life Sciences
Neuroscience
Endocrine and Autonomic Systems
Authors
Temeka Zore, Maria Palafox, Karen Reue,