Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8674184 | Molecular Metabolism | 2018 | 12 Pages |
Abstract
Emerging evidence suggests the role of gut microbiome as a modifier of disease susceptibility due to sex; however, the impact on cardiometabolic disease in this complex interplay is lacking. Elucidating the role of gut microbiome on sex-biased susceptibility in cardiometabolic disease is of high relevance to public health given its high prevalence and significant financial burden.
Keywords
Four core genotypesHDL-CZO-1GPR30IBSLDL-CIBDSHPT2DTMATUDCAMuc2FCGFXRTLR4FMO3NODT1DLPSBAsfarnesoid X receptorApoeapolipoprotein EEstradiolSteroidsEstroneestriolTauroursodeoxycholic acidBile acidscardiovascular diseaseCardiovascular diseasesMetabolic diseaseInflammatory bowel diseasetrimethylamineSex differencesGastrointestinalType 2 diabetesType 1 diabetesNon-obese diabeticCVDirritable bowel syndromesmall heterodimer partnerzonula occludenshigh-density lipoprotein cholesterolLipopolysaccharidesmucin-2Gut microbiotaLow-density lipoprotein cholesterolEstrogen receptorToll-like receptor 4G protein-coupled receptor 30
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Authors
Tzu-Wen L. Cross, Kazuyuki Kasahara, Federico E. Rey,