| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8674207 | Molecular Metabolism | 2018 | 11 Pages |
Abstract
Our results suggest that PPARγ plays neither a tumor suppressive nor oncogenic role in advanced ccRCC, and thus single-agent therapeutics targeting PPARγ are unlikely to be effective for the treatment of this disease. The unique cistrome of PPARγ in ccRCC cells demonstrates the importance of cell type in determining the functions of PPARγ.
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Authors
Danielle J. Sanchez, David J. Steger, Nicolas Skuli, Ankita Bansal, M. Celeste Simon,