| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8674249 | Molecular Metabolism | 2018 | 37 Pages |
Abstract
Nutrient metabolites apparently do not stimulate EC cells of the small intestine directly but through a paracrine mechanism involving GLP-1 secreted from neighboring enteroendocrine cells. In contrast, colonic EC cells are able to sense a multitude of different metabolites generated by the gut microbiota as well as gut hormones, including GLP-1.
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Authors
Mari L. Lund, Kristoffer L. Egerod, Maja S. Engelstoft, Oksana Dmytriyeva, Elvar Theodorsson, Bhavik A. Patel, Thue W. Schwartz,