| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8674261 | Molecular Metabolism | 2018 | 18 Pages |
Abstract
Elevated muscle O-GlcNAc levels paralleled insulin resistance and type 2 diabetes in humans. Moreover, OGT-mediated signaling is necessary for proper skeletal muscle metabolism and whole-body energy homeostasis, and our data highlight O-GlcNAcylation as a potential target for ameliorating metabolic disorders.
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Authors
Hao Shi, Alexander Munk, Thomas S. Nielsen, Morgan R. Daughtry, Louise Larsson, Shize Li, Kasper F. Høyer, Hannah W. Geisler, Karolina Sulek, Rasmus Kjøbsted, Taylor Fisher, Marianne M. Andersen, Zhengxing Shen, Ulrik K. Hansen, Eric M. England,