Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8674350 | Molecular Metabolism | 2018 | 12 Pages |
Abstract
Together, these data demonstrate the metabolic and bioenergetic requirements that enable macrophages to translate tissue oxidation status into either antioxidant or inflammatory responses via sensing OxPL. Targeting dysregulated redox homeostasis in macrophages could therefore lead to novel therapies to treat chronic inflammation.
Keywords
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Authors
Vlad Serbulea, Clint M. Upchurch, Katelyn W. Ahern, Gael Bories, Paxton Voigt, Dory E. DeWeese, Akshaya K. Meher, Thurl E. Harris, Norbert Leitinger,