Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8674354 | Molecular Metabolism | 2018 | 14 Pages |
Abstract
VPS13C is present on BA LDs where is targeted to a distinct subdomain. VPS13C limits the access of ATGL to LD and loss of VPS13C elevates lipolysis and promotes oxidative gene expression.
Keywords
GAPDHVPS13CACADLHADHBPPARGC1APLIN1ABHD5EsrraPPARAHSLLDSBATEbf2peroxisome proliferator-activated receptor gamma coactivator 1-alphaBAsUcp1Brown adipocytesAlphaperoxisome proliferator-activated receptor alphaAtglFree fatty acidsbrown adipose tissueBeta subunitThermogenesisLipid dropletsadipose triglyceride lipasehormone sensitive lipaseuncoupling protein 1Perilipin 1Cideaglyceraldehyde 3-phosphate dehydrogenaseEstrogen related receptor
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Authors
Vanesa D. Ramseyer, Victoria A. Kimler, James G. Granneman,