| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8674363 | Molecular Metabolism | 2018 | 13 Pages |
Abstract
Our findings reveal a novel function of PGC-1α as a suppressor of XBP1s function, suggesting that hepatic PGC-1α promotes gluconeogenesis through multiple pathways as a co-activator for HNF4α and FoxO1 and also as a suppressor for anti-gluconeogenic transcription factor XBP1s.
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Authors
Jaemin Lee, Mario Andrés Salazar Hernández, Thomas Auen, Patrick Mucka, Justin Lee, Umut Ozcan,