Gut microbiome composition in lean patients with NASH is associated with liver damage independent of caloric intake: AÂ prospective pilot study

Article ID	Journal	Published Year	Pages	File Type
8674543	Nutrition, Metabolism and Cardiovascular Diseases	2018	44 Pages	PDF

Abstract

Our preliminary finding of a different pathogenetic process in lean NASH patients needs to be confirmed by larger studies, including those with patient populations stratified by sex and dietary habits.

Keywords

HFD ribosomal RNAs rRNA NAFLD PCoA NAS SCFAs ALT CSS GGT LPS DNA HCC AST Aspartate aminotransferase Alanine aminotransferase nonalcoholic steatohepatitis deoxyribonucleic acid Short chain fatty acids Overweight Nonalcoholic fatty liver disease Principal Coordinates Analysis high-fat diet body mass index BMI Lean Lipopolysaccharides gut microbiome Nash hematoxylin-eosin polymerase chain reaction PCR Obese Hepatocellular carcinoma healthy controls gamma glutamyltransferase

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Gut microbiome composition in lean patients with NASH is associated with liver damage independent of caloric intake: AÂ prospective pilot study

Authors

S.M.B. Duarte, J.T. Stefano, L. Miele, F.R. Ponziani, M. Souza-Basqueira, L.S.R.R. Okada, F.G. de Barros Costa, K. Toda, D.F.C. Mazo, E.C. Sabino, F.J. Carrilho, A. Gasbarrini, C.P. Oliveira,