Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
867662 | Biosensors and Bioelectronics | 2011 | 6 Pages |
Abstract
Reduced graphene oxide (rGO)-modified glassy carbon electrode is used to detect the methicillin-resistant Staphylococcus aureus (MRSA) DNA by using electrochemical impedance spectroscopy. Our experiments confirm that ssDNA, before and after hybridization with target DNA, are successfully anchored on the rGO surface. After the probe DNA, pre-adsorbed on rGO electrode, hybridizes with target DNA, the measured impedance increases dramatically. It provides a new method to detect DNA with high sensitivity (10−13 M, i.e., 100 fM) and selectivity.
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Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Zhijuan Wang, Juan Zhang, Peng Chen, Xiaozhu Zhou, Yanli Yang, Shixin Wu, Li Niu, Yu Han, Lianhui Wang, Peng Chen, Freddy Boey, Qichun Zhang, Bo Liedberg, Hua Zhang,