| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8679382 | Thrombosis Research | 2018 | 35 Pages |
Abstract
DFPP significantly removed high molecular-weight proteins from the haemostatic system and profoundly decreased levels of protein S and TFPI. Overall thrombin-generation balance was only moderately affected in the presence of thrombomodulin. Nevertheless, high depletion of fibrinogen, FXIII and Von Willebrand Factor may expose patients to an increased risk of bleeding.
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Authors
R. Marlu, P. Malvezzi, L. Seyve, T. Jouve, J. Maurizi, F. Defendi, P.L. Carron, M. Christophe, A. Le Gouellec, B. Polack, L. Rostaing,