Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8679448 | Thrombosis Research | 2018 | 8 Pages |
Abstract
EXTEM and FIBTEM CT, ECA and LD-dTT are suitable for measuring the effect of dabigatran in treated patients. In general, results from spiked plasma samples are similar to those of patient samples. Storage of dabigatran plasma samples for up to 12â¯months does not influence measured levels.
Keywords
DTITQDFIBTEMhematologic testsINTEMNOACVKAETPUPLCMRMAPTTHClECACATMCFdabigatranDMSOLC-MS/MSROTEMBlood coagulation testshydrochloric acidanalysis of varianceANOVARotational thromboelastometryMaximum clot firmnessEXTEMstandard errorSEEDimethyl sulfoxideactivated partial thromboplastin timethrombin timeClotting timeprothrombin timeNon-vitamin K antagonist oral anticoagulantsLiquid chromatography-tandem mass spectrometryTissue factorAtrial fibrillationdirect thrombin inhibitormultiple reaction monitoringAnticoagulantsendogenous thrombin potentialUltra-performance liquid chromatography
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Authors
Willemijn J. Comuth, Linda Ã. Henriksen, Daan van de Kerkhof, Steen E. Husted, Steen D. Kristensen, Moniek P.M. de Maat, Anna-Marie B. Münster,