Efficacy of recombinant factor VIIa for severe bleeding complicated by platelet transfusion refractoriness in patients with hematologic malignancies

Article ID	Journal	Published Year	Pages	File Type
8679722	Thrombosis Research	2017	26 Pages	PDF

Abstract

rFVIIa may provide effective and safe hemostasis in patients suffering from severe bleeding and PTR.

Keywords

RBC ISTH rFVIIa HSCT FFP PLT CCI Platelet transfusion refractoriness severe bleeding MDS APTT GvHD DIC AML BSA PTr Human leukocyte antigen HLA Corrected count increment disseminated intravascular coagulation Hematologic malignancy no response overall survival activated partial thromboplastin time prothrombin time body surface area myelodysplastic syndrome recombinant Factor VIIa acute myeloid leukemia Acute lymphoblastic leukemia Acute promyelocytic leukemia ALL Hemoglobin Hemostasis Partial response fresh frozen plasma Platelet Hematopoietic stem cell transplantation red blood cell

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$Efficacy of recombinant factor VIIa for severe bleeding complicated by platelet transfusion refractoriness in patients with hematologic malignancies$

Authors

Tiantian Chu, Yaqiong Tang, Hong Wang, Jiaqian Qi, Ying Zhao, Tingting Pan, Xiaowen Tang, Huiying Qiu, Chengcheng Fu, Changgeng Ruan, De-Pei Wu, Yue Han,