Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8679922 | Alzheimer's & Dementia | 2018 | 8 Pages |
Abstract
Disorders associated with early-life alterations in amyloid precursor protein production or processing are associated with a distinct pattern of early striatal fibrillary Aβ deposition before significant cognitive impairment. A better understanding of this unique pattern could identify important mechanisms of Aβ deposition and possibly important targets for early intervention.
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Authors
Ann D. Cohen, Eric McDade, Brad Christian, Julie Price, Chester Mathis, William Klunk, Benjamin L. Handen,