| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8680062 | Alzheimer's & Dementia | 2017 | 10 Pages |
Abstract
We identified four biologically plausible, candidate plasma biomarkers for dementia. Association of anthranilic acid implicates the kynurenine pathway, which modulates glutamate excitotoxicity. The associations with hypoxanthine and taurine strengthen evidence that uric acid and taurine may be neuroprotective.
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Authors
Vincent Chouraki, Sarah R. Preis, Qiong Yang, Alexa Beiser, Shuo Li, Martin G. Larson, Galit Weinstein, Thomas J. Wang, Robert E. Gerszten, Ramachandran S. Vasan, Sudha Seshadri,