| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8680267 | Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring | 2018 | 7 Pages |
Abstract
MTL tau-PET signal is often associated with abnormal extra-MTL tau-PET signal in CU participants and may represent neurofibrillary tangle development that could identify participants most likely to develop AD dementia. Tau-PET signal exclusively outside of the MTL is seen in 17% of CU participants and could be the initial findings in participants in different AD dementia pathways. Significant (P < .001) differences in tau-standardized uptake value ratio between sides were noted in 26 of 41 examined brain regions implicating further study of side-specific deficits.
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Authors
Val J. Lowe, Tyler J. Bruinsma, Hoon-Ki Min, Emily S. Lundt, Ping Fang, Matthew L. Senjem, Bradley F. Boeve, Keith A. Josephs, Mukesh K. Pandey, Melissa E. Murray, Kejal Kantarci, David T. Jones, Christopher G. Schwarz, David S. Knopman,